Myron S. Cohen, MD, "Hydroxychloroquine for the Prevention of Covid-19 — Searching for Evidence", The New England Journal of Medicine (03 June 2020)
No doubt there will be some people who think I'm being political about this—that I'm "pro-Trump", or "right wing", or "conservative", and therefore have some (hidden?) desire to champion the cause of hydroxychloroquine advocacy—but the simple fact is, I keep banging on about HCQ simply because I suspect it is not being fairly assessed by the scientific establishment, and I "smell a rat". And that bothers me.
It bothers me for people who might be dying because they can't get hold of this stuff (if it works, as I suspect it does), for science (because I see the reputation of science itself being dragged down by the incompetence, or worse, of some in the scientific establishment), and for myself (because, as I've indicated many times before, if I pick up this wretched—probably, in my view, human-manipulated—SARS-CoV-2, I want my doctor to be able to prescribe HCQ (or anything else that he*, in his professional judgement, thinks might help me) without interference from the state.
So, that having been said, here's an interesting article (above) that knocks some of the corners off a recent study (much touted in the MSM as another nail in the coffin of HCQ) by David Boulware, et al, entitiled "A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19", itself published in the NEJM on 03 June 2020.
Contrary to headlines like this one in the Business Insider (just for example), "The first high-quality study of malaria pill hydroxychloroquine just found it doesn't help prevent coronavirus infections", Dr. Cohen's analysis raises several reasons to doubt the precision of Bouleware's trial and concludes with these words:
"The results reported by Boulware et al. are more provocative than definitive, suggesting that the potential prevention benefits of hydroxychloroquine remain to be determined." (emphasis added)
I recommend the article to you. It's quite short and to the point.
(* As it happens my doctor is a "he". I'm not being sexist. I'm also sure he identifies as a "he" too.)