"Chloroquine/ Hydroxychloroquine Prevention of Coronavirus Disease (COVID-19) in the Healthcare Setting (COPCOV)", ClinicalTrials.gov (2020)
Please forgive me if I've missed something here, but I've looked through the protocol for this much-touted global study on the effectiveness of hydroxychloroquine (and chloroquine) as possible preventatives of COVID-19, and I see no mention of zinc. My understanding (and I may be wrong) is that proponents of HCQ typically recommend using HCQ in combination with zinc supplementation, not least because (again, as I understand it, and I may be wrong) HCQ can act as a zinc ionophore. So why—so it appears—is zinc not included?
When I watched one of the accompanying videos by a certain Professor Nick White from the Mahidol Oxford Research Unit in Bangkok, Thailand, it was clear to me that this study is intended to be practical; it's not some merely academic exercise to see how these substances perform on their own. The idea is to see if they can help prevent infection in health workers. As he says:
"Why do we need this trial? We need this trial because, as many of you will have heard—through the press, through the news, and through numerous reports—there are claims that these drugs might be beneficial in COVID-19 infections, in either prevention or treatment. The truth is we really do not know..."
So, that's what it's about—finding out if these drugs "might be beneficial". So, again, if the majority of proponents are using HCQ plus zinc, why is zinc (apparently) not included? Please, if someone knows, do let me know.